Hmm... well... I understand the theory, but struggle with the logic... that is only because you will need the locker in the most extreme situations that will create the most tension. Tension = POP! I know you'll experiment with it, so have fun and keep us posted.
I grenaded a Warn hub on a locked rear full floater kit by giving a little too much gas on pavement. So you are correct, hubs CAN be a fuse! However, the only Super hub we did break, didn't totally let go. It messed up the innards and it had to be replaced, but the hub still held up... front axles though, we have broken 4 times - always when the locker was engaged. Using lockers can increase the rate of fatigue on axle joints, and over time they can weaken and break, even if there is a fuse in place.
As a heads up, I am not sure about Superwinch hubs for Isuzu's, but on our CJ-7, the Super hubs do some strange things when the locker is engaged. The wheel with the most traction is hard to rotate, so what happens is the axle wants to turn and it will turn the hub... but the flange of the hub can put enough force on the mounting bolts to either slowly back them out and/or shear them at the rotor. So may I suggest stepping up to Grade 8 hardware and using loc-tite or some sort of mechanical lock beyond lock washers?